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Advanced Retinol Formulation for Anti-Aging Treatments

P&G Beauty scientists are constantly searching for new active ingredients that provide anti-aging benefits to the skin. Retinoids, derivatives of Vitamin A known for diminishing fine lines and wrinkles and reducing the appearance of photo-aged skin, are key to the anti-aging ingredient arsenal. While all retinoids demonstrate a high degree of efficacy, elevated levels of some retinoids, such as trans-retinoic acid (available by prescription), can cause skin irritation.

With the goal of broader use in anti-aging treatments, P&G Beauty researchers have identified a retinoid formulation that retains efficacy and reduces irritation. The new formulation, retinyl propionate, has demonstrated superior skin improvements with less irritation compared to other active retinoids commonly used in skin care products. Studies show that 0.3% retinyl propionate significantly reduces the appearance of wrinkles and spots after 12 weeks of treatment and compares favorably to treatment with 0.15% retinol. Additionally, retinoid-induced irritation appears to be less evident in retinyl propionate as compared to other active retinoids. Although retinoids are prone to oxidation, retinyl propionate has an improved stability profile, increasing its half-life upon skin during topical delivery. With this new understanding, researchers are incorporating retinyl propionate into P&G Beauty anti-aging treatments.


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