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Genomics Insights Into Healthy Skin

                        P&G Beauty & Grooming scientists are utilizing genomics
                        research to take future product research to a whole new
                        level. When applied to skin health, genomics reveals
                        the underlying biology of aged skin at its most
                        fundamental level, which allows for the identification
                        of new opportunities for intervention.

Innovations in Skin Care Product Development

P&G Beauty & Grooming scientists have explored how skin-related genes function, interact with one another and more importantly, respond to aging and environmental stress at the molecular level. By using genomics tools to map the molecular fingerprint of young vs. old skin, P&G Beauty & Grooming scientists have discovered that the skin's barrier is more important than was ever understood before and we now know that the skin barrier plays a fundamental role in the appearance of aged skin. With this knowledge, P&G Beauty & Grooming scientists have identified unique combinations of cosmetic ingredients and formulated them into cosmetic moisturizers that have great potential to protect and strengthen the stratum corneum in aged skin. Through a continued commitment to beauty science, scientists will explore new fields of skin research to shape the next generation of ingredients focused on an individual's specific skin care needs.  

 Milestones in Genomics Research MILESTONES IN GENOMICS RESEARCH

P&G has successfully used breakthrough genomics research and cutting-edge tools to develop highly advanced skin care products and continues to pave the way for future innovations with a deeper understanding of genomics. Learn more »

Genomics Research at P&G BeautyGENOMICS RESEARCH AT P&G BEAUTY

P&G Beauty & Grooming's rich history in genomics research has provided their scientists access to the leading technologies and capabilities in the field to advance the study of beauty science. Learn more »

Underlying Causes of Skin Aging FoundUNDERLYING CAUSES OF SKIN AGING FOUND

Today, P&G Beauty & Grooming scientists are studying the differences between young and aged skin at the most fundamental level possible - gene expression. Learn more »

Advanced Retinol Formulation for Anti-Aging TreatmentsADVANCED RETINOL FORMULATION FOR ANTI-AGING TREATMENTS

Retinoids, derivatives of Vitamin A known for diminishing fine lines and wrinkles and reducing the appearance of photo-aged skin, are key to the anti-aging ingredient arsenal. Learn more »

Environmental Factors vs. Intrinsic Factors in AgingENVIRONMENTAL FACTORS vs. INTRINSIC FACTORS IN AGING

Although 96% of our skin covers us below the neck, women spend most of their skin-care time and money caring for their faces. As a result, according to most professionals, skin on the rest of the body may be a better indicator of a woman's true age. Learn more »  

Anti-Aging Myths and FactsANTI-AGING MYTHS AND FACTS

Read on to learn more about common anti-aging misconceptions related to wrinkles, genetics and pollution. Learn more » 

In Vitro Cornea and Skin WorkIN VITRO CORNEA AND SKIN WORK

As an innovative leader in science and technology, P&G Beauty & Grooming acknowledges the importance of finding new ways of studying ingredient and product safety and efficacy without the use of animal testing. Learn more »

Niacinamide and Barrier FunctionNIACINAMIDE AND BARRIER FUNCTION

Take a closer look to view cross sections of untreated skin vs. skin treated with a niacinamide-containing body moisturizing lotion. Learn more »

Niacinamide Shown to Increase Tolerance and Effectiveness of Topical Retinoid TherapyNIACINAMIDE SHOWN TO INCREASE TOLERANCE AND EFFECTIVENESS OF TOPICAL RETINOID THERAPY

P&G Beauty & Grooming scientists found that if the skin's barrier could be strengthened, retinoid treatments could be more widely utilized. Learn more »


This pentapeptide, a chain of five amino acids, has been shown to stimulate the synthesis of several proteins found in the skin - including collagen, elastin and fibronectin - in ways typically associated with the skin's natural regenerative process. Learn more »


Recent research indicates that glucosamine may have a variety of applications, including several dermatologic/cosmetic applications. Learn more »

N-Acetyl Glucosamine and HyperpigmentationN-ACETYL GLUCOSAMINE AND HYPERPIGMENTATION

Scientists at P&G Beauty & Grooming have identified an active ingredient - N-acetyl glucosamine - which in small-based clinical testing has been shown to reduce the appearance of hyperpigmentation gently and without irritation. Learn more »

Essential Glucosamine Complex: Redefining Skin AgingESSENTIAL GLUCOSAMINE COMPLEX: REDEFINING SKIN AGING

P&G Beauty & Grooming scientists have developed a breakthrough glucosamine complex designed to penetrate up to 10 surface layers deep to improve the appearance of uneven skin tone caused by an overproduction of melanin from UV radiation. Learn more »


A new ingredient, undecylenoyl phenylalanine, is promising a safe alternative for improved appearance of hyperpigmented skin. Learn more »

Expression of Stratum Corneum Lipid Pathways in Human Skin Equivalent CulturesExpression of Stratum Corneum Lipid Pathways in Human Skin Equivalent Cultures

Presented at the 2008 American Academy of Dermatology annual meeting: Gene pathways involved in stratum corneum lipid formation are expressed in human skin equivalent cultures, suggesting that culture systems derived from either young or older skin cells are appropriate in vitro approaches to study stratum corneum biology. Learn more »

Effects of Topical Moisturizer Application on Stratum Corneum Water Gradient Measured In- Vivo with Confocal Raman MicrospectroscopyEffects of Topical Moisturizer Application on Stratum Corneum Water Gradient Measured In-Vivo with Confocal Raman Microspectroscopy

Presented at the 2008 annual congress of the European Academy of Dermatology Venereology (EADV): Confocal Raman Microspectroscopy (CRM) of human subjects provides non-invasive, real-time, in-vivo measures of molecular concentration profiles. Learn more »

In Vitro Skin Structure Benefits with a New Anti-aging Peptide, Pal-KTIn Vitro Skin Structure Benefits with a New Anti-aging Peptide, Pal-KT

Presented at the 2008 American Academy of Dermatology annual meeting: Pal-KT produces promising in vitro skin responses that are widely believed to be consistent with skin anti-aging benefits. Learn more »

Scientific Advancements in Skin Care

Scientific Advancements in Skin Care 

P&G Beauty & Grooming scientists are using cutting edge genomics and bioinformatics tools to answer the age old question - can old skin be made to look younger? Learn more »

2009 American Academy of Dermatology Annual Meeting: Media Resources


Here you will find information about some of the scientific posters presented at AAD. Learn more »

2009 American Academy for the Advancement of Science Annual Meeting: Media Briefing Book


Here you will find information about some of the scientific posters presented at AAAS. Learn more »

P&G Beauty Science Review: Relevant Ingredient Research 

P&G Beauty Review: Relevant Ingredient Research 

This briefing booklet contains some of the most novel and timely research in the field of skin science today. Learn more »

Professional Alliance for Skin Care Innovation 

The Alliance is an inspired partnership that combines the medical experience of renowned dermatologists from around the world with the fundamental skin aging insights, advanced investigative techniques and formulation knowledge of P&G Beauty & Grooming scientists. Learn more »

Image Gallery

Image gallery 

Images from the Genomics into Healthy Skin research are available for download from our image gallery.

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